Local Anesthesia Materials Articaine Hydrochloride
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Description
Local Anesthesia Powder Articaine hydrochloride CAS 23964-57-0 for Antipain
Product Name: Articaine hydrochloride
Synonyms: methyl 4-methyl-3-[[(1-oxo-2-(propylamino)propyl]amino]-2-thenoate monohydrochloride;CarticaineHCl;Ultracaine;CARTICAINE HYDROCHLORIDE;Ultracain;Articaine hydrochloride;Methyl 4-methyl-3-(2-propylaminopropanoylamino)thiophene-2-carboxylate hydrochloride;4-methyl-3-[2-(propylamino)propanoylamino]thiophene-2-carboxylic acid methyl ester hydrochloride
CAS: 23964-57-0
MF: C13H20N2O3S.ClH
MW: 320.839
EINECS: 245-957-7
Usage Anesthetic;Na+ channel inhibitor
Articaine Applications:
Articaine is a local anaesthetic that has been approved overseas for several years. Like other amide anaesthetics, articaine blocks nerve conduction when it is infiltrated around a nerve. This action is prolonged by combining the drug with a vasoconstrictor such as adrenaline.
The combination of articaine and adrenaline can be used for local or regional anaesthesia for dental procedures. Anaesthesia begins within six minutes and lasts for an hour. The half-life of articaine is approximately 1.8 hours. It is metabolised and then mainly excreted in the urine.
Articaine Clinical use:
1. Articaine is used for pain control. Like other local anesthetic drugs, articaine causes a transient and completely reversible state of anesthesia (loss of sensation) during (dental) procedures.
2. In dentistry, articaine is used both for infiltration and block injections, with the block technique
yielding the greatest duration of anesthesia.
3. In people with hypokalemic sensory overstimulation, lidocaine is not very effective, but articaine
works well.
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